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Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42
β‐amyloid 1‐42 (Aβ1‐42) is a self‐assembling peptide that goes through many conformational and morphological changes before forming the fibrils that are deposited in extracellular plaques characteristic of Alzheimer's disease. The link between Aβ1‐42 structure and toxicity is of major interest,...
Autores principales: | Vadukul, Devkee M., Gbajumo, Oyinkansola, Marshall, Karen E., Serpell, Louise C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363225/ https://www.ncbi.nlm.nih.gov/pubmed/28185264 http://dx.doi.org/10.1002/1873-3468.12590 |
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