Positional Enrichment by Proton Analysis (PEPA): A One‐Dimensional (1)H‐NMR Approach for (13)C Stable Isotope Tracer Studies in Metabolomics

A novel metabolomics approach for NMR‐based stable isotope tracer studies called PEPA is presented, and its performance validated using human cancer cells. PEPA detects the position of carbon label in isotopically enriched metabolites and quantifies fractional enrichment by indirect determination of...

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Detalles Bibliográficos
Autores principales: Vinaixa, Maria, Rodríguez, Miguel A., Aivio, Suvi, Capellades, Jordi, Gómez, Josep, Canyellas, Nicolau, Stracker, Travis H., Yanes, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363230/
https://www.ncbi.nlm.nih.gov/pubmed/28220994
http://dx.doi.org/10.1002/anie.201611347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363230/
https://www.ncbi.nlm.nih.gov/pubmed/28220994
http://dx.doi.org/10.1002/anie.201611347

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