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Antibody-Directed Glucocorticoid Targeting to CD163 in M2-type Macrophages Attenuates Fructose-Induced Liver Inflammatory Changes

Increased consumption of high-caloric carbohydrates contributes substantially to endemic non-alcoholic fatty liver disease in humans, covering a histological spectrum from fatty liver to steatohepatitis. Hypercaloric intake and lipogenetic effects of fructose and endotoxin-driven activation of liver...

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Detalles Bibliográficos
Autores principales: Svendsen, Pia, Graversen, Jonas H., Etzerodt, Anders, Hager, Henrik, Røge, Rasmus, Grønbæk, Henning, Christensen, Erik I., Møller, Holger J., Vilstrup, Hendrik, Moestrup, Søren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363319/
https://www.ncbi.nlm.nih.gov/pubmed/28344991
http://dx.doi.org/10.1016/j.omtm.2016.11.004