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Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy

Umbilical cord blood is a traditional and convenient source of cells for hematopoietic stem cell transplantation. Thymic regulatory T cells (Tregs) are also present in cord blood, and there is growing interest in the use of autologous Tregs to provide a low-risk, fully human leukocyte antigen (HLA)-...

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Detalles Bibliográficos
Autores principales: Seay, Howard R., Putnam, Amy L., Cserny, Judit, Posgai, Amanda L., Rosenau, Emma H., Wingard, John R., Girard, Kate F., Kraus, Morey, Lares, Angela P., Brown, Heather L., Brown, Katherine S., Balavage, Kristi T., Peters, Leeana D., Bushdorf, Ashley N., Atkinson, Mark A., Bluestone, Jeffrey A., Haller, Michael J., Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363324/
https://www.ncbi.nlm.nih.gov/pubmed/28345003
http://dx.doi.org/10.1016/j.omtm.2016.12.003