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Transient receptor potential vanilloid 4 (TRPV4) silencing in Helicobacter pylori‐infected human gastric epithelium

BACKGROUND: Helicobacter pylori (HP) infection induces methylation silencing of specific genes in gastric epithelium. Various stimuli activate the nonselective cation channel TRPV4, which is expressed in gastric epithelium where it detects mechanical stimuli and promotes ATP release. As CpG islands...

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Detalles Bibliográficos
Autores principales: Mihara, Hiroshi, Suzuki, Nobuhiro, Muhammad, Jibran Sualeh, Nanjo, Sohachi, Ando, Takayuki, Fujinami, Haruka, Kajiura, Shinya, Hosokawa, Ayumu, Sugiyama, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363345/
https://www.ncbi.nlm.nih.gov/pubmed/27687509
http://dx.doi.org/10.1111/hel.12361