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Properdin and factor H production by human dendritic cells modulates their T‐cell stimulatory capacity and is regulated by IFN‐γ

Dendritic cells (DCs) and complement are both key members of the innate and adaptive immune response. Recent experimental mouse models have shown that production of alternative pathway (AP) components by DCs strongly affects their ability to activate and regulate T‐cell responses. In this study we i...

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Detalles Bibliográficos
Autores principales: Dixon, Karen O., O'Flynn, Joseph, Klar‐Mohamad, Ngaisah, Daha, Mohamed R., van Kooten, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363362/
https://www.ncbi.nlm.nih.gov/pubmed/28105653
http://dx.doi.org/10.1002/eji.201646703