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A Peroxygenase from Chaetomium globosum Catalyzes the Selective Oxygenation of Testosterone

Unspecific peroxygenases (UPO, EC 1.11.2.1) secreted by fungi open an efficient way to selectively oxyfunctionalize diverse organic substrates, including less‐activated hydrocarbons, by transferring peroxide‐borne oxygen. We investigated a cell‐free approach to incorporate epoxy and hydroxyl functio...

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Detalles Bibliográficos
Autores principales: Kiebist, Jan, Schmidtke, Kai‐Uwe, Zimmermann, Jörg, Kellner, Harald, Jehmlich, Nico, Ullrich, René, Zänder, Daniel, Hofrichter, Martin, Scheibner, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363369/
https://www.ncbi.nlm.nih.gov/pubmed/28103392
http://dx.doi.org/10.1002/cbic.201600677