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Zirconium tetraazamacrocycle complexes display extraordinary stability and provide a new strategy for zirconium-89-based radiopharmaceutical development

We report our initial investigations into the use of tetraazamacrocycles as zirconium-89 chelators. We describe the synthesis and complete characterization of several Zr tetraazamacrocycle complexes, and definitively describe the first crystal structure of zirconium 1,4,7,10-tetraazacyclododecane-1,...

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Detalles Bibliográficos
Autores principales: Pandya, Darpan N., Bhatt, Nikunj, Yuan, Hong, Day, Cynthia S., Ehrmann, Brandie M., Wright, Marcus, Bierbach, Ulrich, Wadas, Thaddeus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363373/
https://www.ncbi.nlm.nih.gov/pubmed/28451334
http://dx.doi.org/10.1039/c6sc04128k