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Targeted Expression of miR-7 Operated by TTF-1 Promoter Inhibited the Growth of Human Lung Cancer through the NDUFA4 Pathway

Targeted expression of gene technique is an important therapeutic strategy for lung cancer. MicroRNA-7 has been well documented as a promising tumor suppressor but never been test in specific gene-promoter-targeted expression in cancer gene therapy. Here, we first evaluated the efficacy of miR-7 exp...

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Detalles Bibliográficos
Autores principales: Lei, Liangyu, Chen, Chao, Zhao, Juanjuan, Wang, HaiRong, Guo, Mengmeng, Zhou, Ya, Luo, Junming, Zhang, Jidong, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363496/
https://www.ncbi.nlm.nih.gov/pubmed/28325285
http://dx.doi.org/10.1016/j.omtn.2016.12.005