RNA-Guided CRISPR-Cas9 System-Mediated Engineering of Acute Myeloid Leukemia Mutations

Current acute myeloid leukemia (AML) disease models face severe limitations because most of them induce un-physiological gene expressions that do not represent conditions in AML patients and/or depend on external promoters for regulation of gene expression/repression. Furthermore, many AML models ar...

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Detalles Bibliográficos
Autores principales: Brabetz, Oliver, Alla, Vijay, Angenendt, Linus, Schliemann, Christoph, Berdel, Wolfgang E., Arteaga, Maria-Francisca, Mikesch, Jan-Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363507/
https://www.ncbi.nlm.nih.gov/pubmed/28325290
http://dx.doi.org/10.1016/j.omtn.2016.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363507/
https://www.ncbi.nlm.nih.gov/pubmed/28325290
http://dx.doi.org/10.1016/j.omtn.2016.12.012

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