Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α

Insulin resistance contributes to the high prevalence of type 2 diabetes mellitus, leading to cardiac anomalies. Emerging evidence depicts a pivotal role for mitochondrial injury in oxidative metabolism and insulin resistance. Mitochondrial aldehyde dehydrogenase (ALDH2) is one of metabolic enzymes...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Ren, Jun, Zhang, Yingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363518/
https://www.ncbi.nlm.nih.gov/pubmed/27634872
http://dx.doi.org/10.18632/oncotarget.11977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363518/
https://www.ncbi.nlm.nih.gov/pubmed/27634872
http://dx.doi.org/10.18632/oncotarget.11977

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