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Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE(−/−) mice

Tet methylcytosine dioxygenase 2 (TET2) mediates the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). The loss of TET2 is associated with advanced atherosclerotic lesions. Our previous study showed that TET2 improves endothelial cell function by enhancing endothelial cell auto...

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Detalles Bibliográficos
Autores principales: Peng, Juan, Yang, Qin, Li, A-Fang, Li, Rong-Qing, Wang, Zuo, Liu, Lu-Shan, Ren, Zhong, Zheng, Xi-Long, Tang, Xiao-Qing, Li, Guo-Hua, Tang, Zhi-Han, Jiang, Zhi-Sheng, Wei, Dang-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363520/
https://www.ncbi.nlm.nih.gov/pubmed/27821816
http://dx.doi.org/10.18632/oncotarget.13121