Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

In this study, the effect of properdistatin, a novel peptide derived from the thrombospondin 1 (TSP-1) domain of properdin, was investigated in three melanoma xenograft models with different TSP-1 expression. The tumors were grown in dorsal window chambers and were treated with 80 mg/kg/day properdi...

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Detalles Bibliográficos
Autores principales: Gaustad, Jon-Vidar, Simonsen, Trude G., Andersen, Lise Mari K., Rofstad, Einar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363551/
https://www.ncbi.nlm.nih.gov/pubmed/27756886
http://dx.doi.org/10.18632/oncotarget.12695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363551/
https://www.ncbi.nlm.nih.gov/pubmed/27756886
http://dx.doi.org/10.18632/oncotarget.12695

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