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Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

Peroxisome proliferator-activating receptor γ (PPARγ), a transcription factor, is involved in many important biological processes, including cell terminal differentiation, survival and apoptosis. However, the role of PPARγ, which regulates tumour promoter and oncogene expression, is not well underst...

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Detalles Bibliográficos
Autores principales: Shu, Yuxin, Lu, Yan, Pang, Xiaojuan, Zheng, Wei, Huang, Yahong, Li, Jiahong, Ji, Jianguo, Zhang, Can, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363564/
https://www.ncbi.nlm.nih.gov/pubmed/27769068
http://dx.doi.org/10.18632/oncotarget.12764