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Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4
Peroxisome proliferator-activating receptor γ (PPARγ), a transcription factor, is involved in many important biological processes, including cell terminal differentiation, survival and apoptosis. However, the role of PPARγ, which regulates tumour promoter and oncogene expression, is not well underst...
Autores principales: | Shu, Yuxin, Lu, Yan, Pang, Xiaojuan, Zheng, Wei, Huang, Yahong, Li, Jiahong, Ji, Jianguo, Zhang, Can, Shen, Pingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363564/ https://www.ncbi.nlm.nih.gov/pubmed/27769068 http://dx.doi.org/10.18632/oncotarget.12764 |
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