Cargando…

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin

Development of innovative more effective therapy is required for refractory osteosarcoma patients. We previously established that glycogen synthase kinase-3β (GSK- 3β) is a therapeutic target in various cancer types. In the present study, we explored the therapeutic efficacy of GSK-3β inhibition aga...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimozaki, Shingo, Yamamoto, Norio, Domoto, Takahiro, Nishida, Hideji, Hayashi, Katsuhiro, Kimura, Hiroaki, Takeuchi, Akihiko, Miwa, Shinji, Igarashi, Kentaro, Kato, Takashi, Aoki, Yu, Higuchi, Takashi, Hirose, Mayumi, Hoffman, Robert M, Minamoto, Toshinari, Tsuchiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363568/
https://www.ncbi.nlm.nih.gov/pubmed/27780915
http://dx.doi.org/10.18632/oncotarget.12781