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Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

Activation of the IFN/STAT1 pathway is closely associated with drug response and recurrence of breast cancer treated by chemotherapy. The aim of the current study was to elucidate the molecular mechanisms involved upstream and downstream of this pathway in order to identify distinct entities that mi...

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Detalles Bibliográficos
Autores principales: Gaston, Julie, Cheradame, Laura, Yvonnet, Vanessa, Deas, Olivier, Poupon, Marie-France, Judde, Jean-Gabriel, Cairo, Stefano, Goffin, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363581/
https://www.ncbi.nlm.nih.gov/pubmed/27791205
http://dx.doi.org/10.18632/oncotarget.12858