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PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach

Melanoma is the most aggressive skin-cancer, showing high mortality at advanced stages. Platelet Derived Growth Factor Receptor-alpha (PDGFR-alpha) potently inhibits melanoma- and endothelium-proliferation and its expression is significantly reduced in melanoma-biopsies, suggesting that melanoma pro...

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Detalles Bibliográficos
Autores principales: D'Arcangelo, Daniela, Facchiano, Francesco, Nassa, Giovanni, Stancato, Andrea, Antonini, Annalisa, Rossi, Stefania, Senatore, Cinzia, Cordella, Martina, Tabolacci, Claudio, Salvati, Annamaria, Tarallo, Roberta, Weisz, Alessandro, Facchiano, Angelo M., Facchiano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363585/
https://www.ncbi.nlm.nih.gov/pubmed/27764787
http://dx.doi.org/10.18632/oncotarget.12629