MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

We aimed to elucidate the effect of JQ1, a BET inhibitor, on small cell lung cancers (SCLCs) with MYCL amplification and/or expression. Fourteen SCLC cell lines, including four with MYCL amplification, were examined for the effects of JQ1 on protein and gene expression by Western blot and mRNA micro...

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Detalles Bibliográficos
Autores principales: Kato, Fuyumi, Fiorentino, Francesco Paolo, Alibés, Andreu, Perucho, Manuel, Sánchez-Céspedes, Montse, Kohno, Takashi, Yokota, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363592/
https://www.ncbi.nlm.nih.gov/pubmed/27764802
http://dx.doi.org/10.18632/oncotarget.12671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363592/
https://www.ncbi.nlm.nih.gov/pubmed/27764802
http://dx.doi.org/10.18632/oncotarget.12671

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