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Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

Here, we evaluated the expression of CYP24A1, a protein that inactivates vitamin D in tissues. CYP24A1 expression was increased in advanced-stage endometrial tumors compared to normal tissues. Similarly, endometrial cancer cells expressed higher levels of CYP24A1 than immortalized endometrial epithe...

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Detalles Bibliográficos
Autores principales: Bokhari, Amber A., Lee, Laura R., Raboteau, Dewayne, Turbov, Jane, Rodriguez, Isabel V., Pike, John Wesley, Hamilton, Chad A., Maxwell, George Larry, Rodriguez, Gustavo C., Syed, Viqar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363606/
https://www.ncbi.nlm.nih.gov/pubmed/27769055
http://dx.doi.org/10.18632/oncotarget.12725