Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

Neuroblastoma is the most frequent, extracranial solid tumor in children with still poor prognosis in stage IV disease. In this study, we analyzed FOXO3-phosphorylation and cellular localization in tumor biopsies and determined the function of this homeostasis regulator in vitro and in vivo. FOXO3-p...

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Detalles Bibliográficos
Autores principales: Hagenbuchner, Judith, Rupp, Martina, Salvador, Christina, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Geiger, Kathrin, Sergi, Consolato, Obexer, Petra, Ausserlechner, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363607/
https://www.ncbi.nlm.nih.gov/pubmed/27769056
http://dx.doi.org/10.18632/oncotarget.12728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363607/
https://www.ncbi.nlm.nih.gov/pubmed/27769056
http://dx.doi.org/10.18632/oncotarget.12728

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