Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain

Icsbp/Irf8 is an interferon regulatory transcription factor that functions as a suppressor of myeloid leukemias. Consistent with this activity, Icsbp represses a set of genes encoding proteins that promote cell proliferation/survival. One such gene encodes Gas2, a calpain inhibitor. We previously fo...

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Detalles Bibliográficos
Autores principales: Hjort, Elizabeth E., Huang, Weiqi, Hu, Liping, Eklund, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363610/
https://www.ncbi.nlm.nih.gov/pubmed/27769062
http://dx.doi.org/10.18632/oncotarget.12749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363610/
https://www.ncbi.nlm.nih.gov/pubmed/27769062
http://dx.doi.org/10.18632/oncotarget.12749

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