Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

The Hippo pathway regulates the down-stream target Yes-associated protein (YAP) to maintain organ homeostasis, which is commonly inactivated in many types of cancers. However, how cell adhesion dysregulates the Hippo pathway activating YAP oncogene in hepatocellular carcinoma (HCC) remains unclear....

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Detalles Bibliográficos
Autores principales: Wong, Kwong-Fai, Liu, Angela M., Hong, Wanjin, Xu, Zhi, Luk, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363613/
https://www.ncbi.nlm.nih.gov/pubmed/27765911
http://dx.doi.org/10.18632/oncotarget.12760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363613/
https://www.ncbi.nlm.nih.gov/pubmed/27765911
http://dx.doi.org/10.18632/oncotarget.12760

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