Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

SPARC is a matrix protein that mediates interactions between cells and the microenvironment. In cancer, SPARC may either promote or inhibit tumor growth depending upon the tumor type. In neuroblastoma, SPARC is expressed in the stromal Schwannian cells and functions as a tumor suppressor. Here, we d...

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Detalles Bibliográficos
Autores principales: Chlenski, Alexandre, Dobratic, Marija, Salwen, Helen R., Applebaum, Mark, Guerrero, Lisa J., Miller, Ryan, DeWane, Gillian, Solomaha, Elena, Marks, Jeremy D., Cohn, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363614/
https://www.ncbi.nlm.nih.gov/pubmed/27776337
http://dx.doi.org/10.18632/oncotarget.12773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363614/
https://www.ncbi.nlm.nih.gov/pubmed/27776337
http://dx.doi.org/10.18632/oncotarget.12773

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