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PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection
Macrophage plasticity is critical for controlling inflammation including those produced by helminth infections, where alternatively activated macrophages (AAM) are accumulated in tissues. AAM expressing the co-inhibitory molecule programmed death ligand 2 (PD-L2), which is capable of binding program...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363616/ https://www.ncbi.nlm.nih.gov/pubmed/27783986 http://dx.doi.org/10.18632/oncotarget.12790 |