PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

Macrophage plasticity is critical for controlling inflammation including those produced by helminth infections, where alternatively activated macrophages (AAM) are accumulated in tissues. AAM expressing the co-inhibitory molecule programmed death ligand 2 (PD-L2), which is capable of binding program...

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Detalles Bibliográficos
Autores principales: Stempin, Cinthia C., Motrán, Claudia C., Aoki, María P., Falcón, Cristian R., Cerbán, Fabio M., Cervi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363616/
https://www.ncbi.nlm.nih.gov/pubmed/27783986
http://dx.doi.org/10.18632/oncotarget.12790

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