MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA

Histone H2AX is a tumor suppressor protein that plays an important role in apoptosis. However, the mechanism underlying the association of H2AX with apoptosis in cancer cells remains elusive. Here, we showed that H2AX knockdown in lung cancer A549 cells affected the expression of 16 microRNAs (miRNA...

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Detalles Bibliográficos
Autores principales: Xu, Chengshan, Zhang, Ling, Duan, Lianning, Lu, Chengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363619/
https://www.ncbi.nlm.nih.gov/pubmed/27780918
http://dx.doi.org/10.18632/oncotarget.12794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363619/
https://www.ncbi.nlm.nih.gov/pubmed/27780918
http://dx.doi.org/10.18632/oncotarget.12794

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