Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors

In many forms of cancer the signal transducer and activator of transcription 3 (STAT3) transcription factor remains constitutively active, driving cancer survival and progression. The critical role of STAT3 in tumorigenesis has prompted a campaign of drug discovery programs to identify small molecul...

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Detalles Bibliográficos
Autores principales: Furtek, Steffanie L., Matheson, Christopher J., Backos, Donald S., Reigan, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363639/
https://www.ncbi.nlm.nih.gov/pubmed/27793003
http://dx.doi.org/10.18632/oncotarget.12868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363639/
https://www.ncbi.nlm.nih.gov/pubmed/27793003
http://dx.doi.org/10.18632/oncotarget.12868

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