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HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

Pancreatic cancer is one of the most aggressive solid malignancies prone to metastasis. Epithelial-mesenchymal transition (EMT) contributes to cancer invasiveness and drug resistance. In this study, we investigated whether HS-173, a novel PI3K inhibitor blocked the process of EMT in pancreatic cance...

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Detalles Bibliográficos
Autores principales: Rumman, Marufa, Jung, Kyung Hee, Fang, Zhenghuan, Yan, Hong Hua, Son, Mi Kwon, Kim, Soo Jung, Kim, Juyoung, Park, Jung Hee, Lim, Joo Han, Hong, Sungwoo, Hong, Soon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363641/
https://www.ncbi.nlm.nih.gov/pubmed/27793006
http://dx.doi.org/10.18632/oncotarget.12871