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Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks

The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-associated proteins) technology enables rapid and precise genome editing at any desired genomic position in almost all cells and organisms. In this study, we analyzed the impact of different repair templates on the frequency o...

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Detalles Bibliográficos
Autores principales: Song, Fei, Stieger, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363683/
https://www.ncbi.nlm.nih.gov/pubmed/28624224
http://dx.doi.org/10.1016/j.omtn.2017.02.006