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Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks
The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-associated proteins) technology enables rapid and precise genome editing at any desired genomic position in almost all cells and organisms. In this study, we analyzed the impact of different repair templates on the frequency o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363683/ https://www.ncbi.nlm.nih.gov/pubmed/28624224 http://dx.doi.org/10.1016/j.omtn.2017.02.006 |