Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer

The human HOXB13 gene encodes a 284 amino acid transcription factor belonging to the homeobox gene family containing a homeobox and a HoxA13 N-terminal domain. It is highly linked to hereditary prostate cancer, the majority of which is manifested as a result of a Single Nucleotide Polymorphism (SNP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandrasekaran, Gopalakrishnan, Hwang, Eu Chang, Kang, Taek Won, Kwon, Dong Deuk, Park, Kwangsung, Lee, Je-Jung, Lakshmanan, Vinoth-Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363706/
https://www.ncbi.nlm.nih.gov/pubmed/28272408
http://dx.doi.org/10.1038/srep43830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363706/
https://www.ncbi.nlm.nih.gov/pubmed/28272408
http://dx.doi.org/10.1038/srep43830

Ejemplares similares