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Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke

Stroke is a disease in dire need of better therapies. We have previously shown that a fragment of the extracellular matrix proteoglycan, perlecan, has beneficial effects following cerebral ischemia via the α5β1 integrin receptor. We now report that endothelial cell selective α5 integrin deficient mi...

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Detalles Bibliográficos
Autores principales: Roberts, Jill, de Hoog, Leon, Bix, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363730/
https://www.ncbi.nlm.nih.gov/pubmed/26661237
http://dx.doi.org/10.1177/0271678X15616979