Pre-clinical Assessment of C134, a Chimeric Oncolytic Herpes Simplex Virus, in Mice and Non-human Primates

Oncolytic herpes simplex virus (oHSV) type I constructs are investigational anti-neoplastic agents for a variety of malignancies, including malignant glioma. Clinical trials to date have supported the safety of these agents even when directly administered in the CNS. Traditional pre-clinical US Food...

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Detalles Bibliográficos
Autores principales: Cassady, Kevin A., Bauer, David F., Roth, Justin, Chambers, Melissa R., Shoeb, Trent, Coleman, Jennifer, Prichard, Mark, Gillespie, G. Yancey, Markert, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363760/
https://www.ncbi.nlm.nih.gov/pubmed/28345027
http://dx.doi.org/10.1016/j.omto.2017.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363760/
https://www.ncbi.nlm.nih.gov/pubmed/28345027
http://dx.doi.org/10.1016/j.omto.2017.02.001

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