Early Detection of Acute Drug-Induced Liver Injury in Mice by Noninvasive Near-Infrared Fluorescence Imaging

Hepatocellular and cholestatic forms of drug-induced liver injury (DILI) are major reasons for late-stage termination of small-molecule drug discovery research projects. Biochemical serum markers are limited in their ability to sensitively and specifically detect both of these common DILI forms in p...

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Detalles Bibliográficos
Autores principales: Vasquez, Kristine O., Peterson, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363778/
https://www.ncbi.nlm.nih.gov/pubmed/28115551
http://dx.doi.org/10.1124/jpet.116.238378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363778/
https://www.ncbi.nlm.nih.gov/pubmed/28115551
http://dx.doi.org/10.1124/jpet.116.238378

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