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Distance in cancer gene expression from stem cells predicts patient survival

The degree of histologic cellular differentiation of a cancer has been associated with prognosis but is subjectively assessed. We hypothesized that information about tumor differentiation of individual cancers could be derived objectively from cancer gene expression data, and would allow creation of...

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Detalles Bibliográficos
Autores principales: Riester, Markus, Wu, Hua-Jun, Zehir, Ahmet, Gönen, Mithat, Moreira, Andre L., Downey, Robert J., Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363813/
https://www.ncbi.nlm.nih.gov/pubmed/28333954
http://dx.doi.org/10.1371/journal.pone.0173589