Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity

Sitagliptin is selective dipeptidyl peptidase-4 inhibitor (DPP4-I), used clinically as a new oral anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective role of sitagliptin pretreatment against methotrexate (MTX) induced hepatotoxicity in mice. Forty mice were div...

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Detalles Bibliográficos
Autores principales: Abo-Haded, Hany M., Elkablawy, Mohamed A., Al-johani, Zeyad, Al-ahmadi, Osama, El-Agamy, Dina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363865/
https://www.ncbi.nlm.nih.gov/pubmed/28334048
http://dx.doi.org/10.1371/journal.pone.0174295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363865/
https://www.ncbi.nlm.nih.gov/pubmed/28334048
http://dx.doi.org/10.1371/journal.pone.0174295

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