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Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity

Sitagliptin is selective dipeptidyl peptidase-4 inhibitor (DPP4-I), used clinically as a new oral anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective role of sitagliptin pretreatment against methotrexate (MTX) induced hepatotoxicity in mice. Forty mice were div...

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Detalles Bibliográficos
Autores principales:	Abo-Haded, Hany M., Elkablawy, Mohamed A., Al-johani, Zeyad, Al-ahmadi, Osama, El-Agamy, Dina S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363865/ https://www.ncbi.nlm.nih.gov/pubmed/28334048 http://dx.doi.org/10.1371/journal.pone.0174295

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