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Clinical validation of chemotherapy predictors developed on global microRNA expression in the NCI60 cell line panel tested in ovarian cancer

OBJECTIVE: Ovarian cancer is the leading cause of death among gynecologic malignancies. This is partly due to a non-durable response to chemotherapy. Prediction of resistance to chemotherapy could be a key role in more personalized treatment. In the current study we aimed to examine if microRNA base...

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Detalles Bibliográficos
Autores principales: Prahm, Kira Philipsen, Høgdall, Claus, Karlsen, Mona Aarenstrup, Christensen, Ib Jarle, Novotny, Guy Wayne, Knudsen, Steen, Hansen, Anker, Jensen, Peter Buhl, Jensen, Thomas, Mirza, Mansoor Raza, Ekmann-Gade, Anne Weng, Nedergaard, Lotte, Høgdall, Estrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363866/
https://www.ncbi.nlm.nih.gov/pubmed/28334047
http://dx.doi.org/10.1371/journal.pone.0174300