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Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide, but is still lacking sensitive and specific biomarkers for early diagnosis and prognosis. In this study, we applied targeted massively parallel semiconductor sequencing to assess methylation on a panel of genes...

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Detalles Bibliográficos
Autores principales: Holmila, Reetta, Sklias, Athena, Muller, David C., Degli Esposti, Davide, Guilloreau, Paule, Mckay, James, Sangrajrang, Suleeporn, Srivatanakul, Petcharin, Hainaut, Pierre, Merle, Philippe, Herceg, Zdenko, Nogueira da Costa, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363871/
https://www.ncbi.nlm.nih.gov/pubmed/28333958
http://dx.doi.org/10.1371/journal.pone.0174265