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Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide, but is still lacking sensitive and specific biomarkers for early diagnosis and prognosis. In this study, we applied targeted massively parallel semiconductor sequencing to assess methylation on a panel of genes...
Autores principales: | Holmila, Reetta, Sklias, Athena, Muller, David C., Degli Esposti, Davide, Guilloreau, Paule, Mckay, James, Sangrajrang, Suleeporn, Srivatanakul, Petcharin, Hainaut, Pierre, Merle, Philippe, Herceg, Zdenko, Nogueira da Costa, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363871/ https://www.ncbi.nlm.nih.gov/pubmed/28333958 http://dx.doi.org/10.1371/journal.pone.0174265 |
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