The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats

OBJECTIVE: The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal formulation of this combination. METHODS: QX...

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Detalles Bibliográficos
Autores principales: Yin, Qinqin, Li, Jun, Zheng, Qingshan, Yang, Xiaolin, Lv, Rong, Ma, Longxiang, Liu, Jin, Zhu, Tao, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363931/
https://www.ncbi.nlm.nih.gov/pubmed/28334014
http://dx.doi.org/10.1371/journal.pone.0174421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363931/
https://www.ncbi.nlm.nih.gov/pubmed/28334014
http://dx.doi.org/10.1371/journal.pone.0174421

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