Metformin inhibits gastric cancer cells metastatic traits through suppression of epithelial-mesenchymal transition in a glucose-independent manner

Epithelial-mesenchymal transition (EMT), which is mainly recognized by upregulation of mesenchymal markers and movement of cells, is a critical stage occurred during embryo development and spreading cancerous cells. Metformin is an antidiabetic drug used in treatment of type 2 diabetes. EMT inhibito...

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Detalles Bibliográficos
Autores principales: Valaee, Shiva, Yaghoobi, Mohammad Mehdi, Shamsara, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363973/
https://www.ncbi.nlm.nih.gov/pubmed/28334027
http://dx.doi.org/10.1371/journal.pone.0174486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363973/
https://www.ncbi.nlm.nih.gov/pubmed/28334027
http://dx.doi.org/10.1371/journal.pone.0174486

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