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Metformin inhibits gastric cancer cells metastatic traits through suppression of epithelial-mesenchymal transition in a glucose-independent manner
Epithelial-mesenchymal transition (EMT), which is mainly recognized by upregulation of mesenchymal markers and movement of cells, is a critical stage occurred during embryo development and spreading cancerous cells. Metformin is an antidiabetic drug used in treatment of type 2 diabetes. EMT inhibito...
Autores principales: | Valaee, Shiva, Yaghoobi, Mohammad Mehdi, Shamsara, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363973/ https://www.ncbi.nlm.nih.gov/pubmed/28334027 http://dx.doi.org/10.1371/journal.pone.0174486 |
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