Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer

Tumours are comprised of a highly heterogeneous population of cells, of which only a small subset of stem-like cells possess the ability to regenerate tumours in vivo. These cancer stem cells (CSCs) represent a significant clinical challenge as they are resistant to conventional cancer therapies and...

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Detalles Bibliográficos
Autores principales: Witt, A E, Lee, C-W, Lee, T I, Azzam, D J, Wang, B, Caslini, C, Petrocca, F, Grosso, J, Jones, M, Cohick, E B, Gropper, A B, Wahlestedt, C, Richardson, A L, Shiekhattar, R, Young, R A, Ince, T A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364039/
https://www.ncbi.nlm.nih.gov/pubmed/27694895
http://dx.doi.org/10.1038/onc.2016.337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364039/
https://www.ncbi.nlm.nih.gov/pubmed/27694895
http://dx.doi.org/10.1038/onc.2016.337

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