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Cell-cycle coupled expansion of AR activity promotes cancer progression

The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablation of AR activity is the first line of therapeutic intervention for disseminated disease. While initially effective, recurrent tumors ultimately arise for which there is no durable cure. Despite the...

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Detalles Bibliográficos
Autores principales: McNair, Christopher, Urbanucci, Alfonso, Comstock, Clay E.S., Augello, Michael A., Goodwin, Jonathan F., Launchbury, Rosalind, Zhao, Shuang, Schiewer, Mathew J., Ertel, Adam, Karnes, Jeffrey, Davicioni, Elai, Wang, Liguo, Wang, Qianben, Mills, Ian G., Feng, Felix Y., Li, Wei, Carroll, Jason S., Knudsen, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364060/
https://www.ncbi.nlm.nih.gov/pubmed/27669432
http://dx.doi.org/10.1038/onc.2016.334