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Cell-cycle coupled expansion of AR activity promotes cancer progression
The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablation of AR activity is the first line of therapeutic intervention for disseminated disease. While initially effective, recurrent tumors ultimately arise for which there is no durable cure. Despite the...
Autores principales: | McNair, Christopher, Urbanucci, Alfonso, Comstock, Clay E.S., Augello, Michael A., Goodwin, Jonathan F., Launchbury, Rosalind, Zhao, Shuang, Schiewer, Mathew J., Ertel, Adam, Karnes, Jeffrey, Davicioni, Elai, Wang, Liguo, Wang, Qianben, Mills, Ian G., Feng, Felix Y., Li, Wei, Carroll, Jason S., Knudsen, Karen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364060/ https://www.ncbi.nlm.nih.gov/pubmed/27669432 http://dx.doi.org/10.1038/onc.2016.334 |
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