Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [(11)C]CB184, in healthy human volunteers

BACKGROUND: N,N-di-n-propyl-2-[2-(4-[(11)C]methoxyphenyl)-6,8-dichloroimidazol[1,2-a]pyridine-3-yl]acetamide ([(11)C]CB184) is a novel selective radioligand for the 18-kD translocator protein (TSPO), which is upregulated in activated microglia in the brain, and may be useful in positron emission tom...

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Detalles Bibliográficos
Autores principales: Sakata, Muneyuki, Ishibashi, Kenji, Imai, Masamichi, Wagatsuma, Kei, Ishii, Kenji, Hatano, Kentaro, Ishiwata, Kiichi, Toyohara, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364125/
https://www.ncbi.nlm.nih.gov/pubmed/28337723
http://dx.doi.org/10.1186/s13550-017-0271-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364125/
https://www.ncbi.nlm.nih.gov/pubmed/28337723
http://dx.doi.org/10.1186/s13550-017-0271-6

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