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Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [(11)C]CB184, in healthy human volunteers
BACKGROUND: N,N-di-n-propyl-2-[2-(4-[(11)C]methoxyphenyl)-6,8-dichloroimidazol[1,2-a]pyridine-3-yl]acetamide ([(11)C]CB184) is a novel selective radioligand for the 18-kD translocator protein (TSPO), which is upregulated in activated microglia in the brain, and may be useful in positron emission tom...
Autores principales: | Sakata, Muneyuki, Ishibashi, Kenji, Imai, Masamichi, Wagatsuma, Kei, Ishii, Kenji, Hatano, Kentaro, Ishiwata, Kiichi, Toyohara, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364125/ https://www.ncbi.nlm.nih.gov/pubmed/28337723 http://dx.doi.org/10.1186/s13550-017-0271-6 |
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