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Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania (Viannia) Subgenus

The growing resistance of leishmaniasis to first-line drugs like antimonials in some regions limits the control of this parasitic disease. The precise mechanisms involved in Leishmania antimony resistance are still subject to debate. The reduction of intracellular Sb(III) accumulation is a common ch...

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Detalles Bibliográficos
Autores principales: dos Reis, Priscila G., do Monte-Neto, Rubens L., Melo, Maria N., Frézard, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364148/
https://www.ncbi.nlm.nih.gov/pubmed/28393067
http://dx.doi.org/10.3389/fcell.2017.00024